A POOLED PARACOLOBACTRUM INTERMEDIUM ANTISERUM FOR SCREENING IN ENTERIC BACTERIOLOGY

A Pooled Paracolobactrum Intermedium Antiserum for Screening in Enteric Bacteriology.

Recent investigations of the antigenic relationships of all Paracolobactrum cultures isolated in the Florida State Board of Health, Jacksonville, laboratory during 1946 and 1947 (Stuart, Galton, and McGann: J. Bact., 46, 411, 1948) revealed that 40 per cent of these cultures were Paracolobactrum intermedium. It was also found that many of the P. intermedium cultures belonged to the Bethesda gro...

Antigenic relationships of 764 Paracolobactrum intermedium cultures.

passivity in waiting for godot and endgame: a psychoanalytic reading

this study intends to investigate samuel beckett’s waiting for godot and endgame under the lacanian psychoanalysis. it begins by explaining the most important concepts of lacanian psychoanalysis. the beckettian characters are studied regarding their state of unconscious, and not the state of consciousness as is common in most beckett studies. according to lacan, language plays the sole role in ...

Pooled Screening for Synergistic Interactions Subject to Blocking and Noise

The complex molecular networks in the cell can give rise to surprising interactions: gene deletions that are synthetically lethal, gene overexpressions that promote stemness or differentiation, synergistic drug interactions that heighten potency. Yet, the number of actual interactions is dwarfed by the number of potential interactions, and discovering them remains a major problem. Pooled screen...

Pooled screening for anti-proliferative inhibitors of protein-protein interactions

Protein-protein interactions (PPIs) are emerging as a promising new class of drug targets. Here, we present a novel high-throughput approach to screen inhibitors of PPIs in cells. We designed a library of 50,000 human peptide-binding motifs and used a pooled lentiviral system to express them intracellularly and screen for their effects on cell proliferation. We thereby identified inhibitors tha...